Presence of neuropathology among a sample of individuals with bipolar 
   Lead Investigator:    Ben Peckham
   Institution      :    University of Calgary
   E-Mail           :    stephen.peckham@ucalgary.ca
   Proposal ID      :    1647



   Proposal Description:
   The requested data will be used to generate descriptive statistics of a sample  of individuals diagnosed with bipolar disorder (BD) who also have autopsy data  available. Basic demographics (i.e., sex, age at death, age at final assessment  prior to death, ethnicity) will be reported as well as the cognitive status and  the relative frequency of Alzheimer???s disease (AD), vascular dementia (VaD),  hippocampal sclerosis (HS), Lewy Body disease (LBD), and frontotemporal  dementia (FTD) from the sample???s last visit before death. The proposed study  will elucidate the relatively unknown area of neuropathological development of  the aging brain affected by BD. The findings may yield important implications  for clinicians and researchers in understanding the long-term cognitive  progression of individuals with BD as they progress into later life.